Caroline Sartain, Ph.D., is a principal cellular profiling scientist at UL Research Institutes’ Chemical Insights. She leads the development of a high-throughput phenotypic and transcriptomic cell profiling platform that will be leveraged to generate bioactivity signatures for hundreds to thousands of understudied chemicals. In this role, she provides strategic and technical leadership in assay design, high-throughput laboratory workflow efficiency, and high-dimensional data analysis and management to establish and expand UL Research Institutes’ in vitro chemical bioactivity data portfolio. 

Caroline is a seasoned developer of advanced high-throughput laboratory platforms, with deep experience building and deploying next-generation sequencing and imaging-based assays across the diagnostics, small-molecule therapeutics, and biotechnology sectors. Her work spans diverse areas of human health, including oncology (liver cancer and cancer immunotherapy), rare genetic disease (carrier screening and therapeutic development for muscular dystrophy, cardiomyopathy, and sickle cell disease), and reproductive medicine (preimplantation genetic screening). Across these applications, she has integrated specialized techniques, including single-cell sequencing, liquid biopsy biomarker detection, and design of custom-built laboratory robotics to translate complex biological data into scalable, operational platforms that support discovery and decision-making. 

Caroline received her Ph.D. in Genetics, Genomics, & Development from Cornell University and her Bachelor of Science in Biochemistry & Molecular Biology from Rhodes College. 

ORCiD: 0009-0004-2586-8743